Why genes overlap in viruses

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Why genes overlap in viruses

The genomes of most virus species have overlapping genes--two or more proteins coded for by the same nucleotide sequence. Several explanations have been proposed for the evolution of this phenomenon, and we test these by comparing the amount of gene overlap in all known virus species. We conclude that gene overlap is unlikely to have evolved as a way of compressing the genome in response to the...

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The intimate relationships of viruses and genes have been proper subjects of speculation for many years. More recently, genetic studies, especially on bacteriophages and bacteria have given concrete substance to some of these speculations. For this occasion a brief didactic review of some relevant experimental findings may be appropriate. The support that they can give to concept and methodolog...

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Overlap syndrome, which is known as the coexistence of chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA), was first defined by Flenley. Although it can refer to concomitant occurrence of any of the pulmonary diseases and OSA, overlap syndrome is commonly considered as the coexistence of OSA and COPD. This disease has unique adverse health consequences distinct from ...

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ژورنال

عنوان ژورنال: Proceedings of the Royal Society B: Biological Sciences

سال: 2010

ISSN: 0962-8452,1471-2954

DOI: 10.1098/rspb.2010.1052